Botox Approved for Urinary Incontinence

FDA approved Botox for Multiple Sclerosis induced incontinence. Time Magazine published an article Wednesday.

What exactly is Botox?

Famous as a symbol of vanity, Botox is an abbreviation for Botulinum Toxin which actually has medicinal uses. Botox is FDA approved to treat chronic migraines, muscle problems, underarm sweating and a number of other conditions. Now add to that, urinary incontinence.

On Wednesday, the U.S. Food and Drug Administration (FDA) approved Botox to treat incontinence in patients with neurological conditions like spinal cord injury and multiple sclerosis.

Botox, a muscle-relaxing medication used to decrease spasticity related to multiple sclerosis and other neurological conditions. Botox is derived from the bacterium Clostridium botulinum and is in a class of drugs called neurotoxins. There are three types of botulinum toxins available for therapeutic use:

• OnabotulinumtoxinA (Botox/Botox Cosmetic)
• RimabotulinumtoxinB (Myobloc)
• AbobotulinumtoxinA (Dysport)

OnabotulinumtoxinA is the Botox approved for urinary incontinence.

How does it treat urinary incontinence? In some patients with neurological conditions, over activity in the bladder leads to an inability to store urine. By injecting Botox directly into the bladder to relax it, patients are offered more muscle control and less incontinence.

In two clinical trials involving 691 patients with incontinence due to spinal cord injury or multiple sclerosis, those who got Botox had a significant reduction in weekly incontinence episodes, compared to a placebo group, the FDA said. The most common adverse effects were urinary tract infection and urinary retention.

Given that incontinence is so difficult to manage — typically involving drugs to relax the bladder and the use of a catheter to empty it — Botox may give some patients another option.

One injection may help control incontinence for up to 10 months, the FDA said.

The approval also opens the door to yet more uses for Botox, made by Allergan, the New York Times reported.

The drug has been studied for more than 100 medical conditions in all, according to Caroline Van Hove, company spokeswoman. “Anything from writer’s cramp to anal fissure to Parkinson’s disease. That’s why we say it’s a pipeline in a vial,” she said Wednesday.

In my mind, urinary incontinence is the ultimate embarrassment living a life with multiple sclerosis

I thought this medication might possibly work to lessen this problem and save my ego, but with further research I learned that Botox is a treatment only used as a last resort! Botox actually weakens the bladder and is only tried after a suprapubic Catheter has been used.

I guess I’m back to the embarrassment products. I’m grateful I was told of a product that can be sent to my house with Free Shipping!

Linda

About our Co-Founder: With a bachelors in Social Work, Linda is 53 years old, happily married with eight children and 17 grandchildren. Diagnosed with MS in 1995 and now having accepted and truly embraced her new reality, Linda has created MSrelief.com. She is dedicated to proving that joy can be chosen while living with Multiple Sclerosis. Linda specializes in helping others, especially those with MS attain the lifestyle, independence and happiness amid living with MS.

9 Comments:

  1. I don’t know that Botulinum Toxin has a positive health effect to the urinary function of an individual. This discovery will serve as a big help to the treatment of urinary incontinence. This gives new hope to those individuals who are suffering from this disturbing medical condition.

  2. As soon as I started reading I got excited to learn that Botox is a potential cure for incontinence. But it was really heart breaking to know that it is only being used for patients already using a suprapubic Catheter.
    It is good to learn that researches are ongoing in the field for curing incontinence by eliminating the causes. And thanks for mentioning Linda.

    • Arvind,
      I was right there with you! When I first learned that Botox might be an aide, I was so hopeful! Then the blast~ oh well, it is what it is and we’re doing our best!
      Linda

  3. Although it is clinically proven that it is effective in treating urinary incontinence, how about its safety? I would like to know if Botox may cause adverse health effects to the user or even allergic reactions.

    • Andy,
      Yes, it’s not as good as I thought! When I researched further, Botox is only suggested as a last resort! It is indeed too dangerous!
      Linda

  4. Estel,
    I’d love to hear about your challenge!
    Linda

  5. My sister’s long plastic tubing stays twisted and looped. Is there anything to be sprayed or wiped on the tubing to prevent this? She has tried wax and soap. Neither worked. Thank you.

    • I’m sorry to say that I don’t know the answer to this. I’ll ask my partners and get back with you tomorrow.
      Linda

    • I’m so sorry it took me over a week to get back with you!!! I talked with my partner and she doesn’t know any more than I do! I suggest you talk with the provider who gave your sister her equipment. Most likely they will have suggestions of a product that will help with this problem. I’d appreciate it if you’d come back and tell us what they said! Others are probably having the same problem!
      Linda

Comments are closed