Bean’s Blog ~ Miracle Cream for Injectable MS Pharmaceuticals

by Caroline Kyriakou

It came to be known to me as the Miracle Cream! When I was first diagnosed with MS in 2006, I didn’t know anything about it. I learned quickly through books and the internet.

I was disappointed that the only MS therapies available were injectables.

I really didn’t like needles (I still don’t) but it was important to me to start on a therapy as soon as possible. My neurologist and I decided on Avonex, a weekly Intramuscular injection. I was given a DVD to watch and was told a nurse would come to my home to teach me and Abe, my husband, how to give the shots. We bought oranges and were ready to practice with the nurse as I would be receiving my first injection.

At first it didn’t seem so bad when it was the orange getting an inch and half needle piecing through its skin. When it came to my turn, however, I quickly learned I had a fear of needles. I had gotten shots at my doctor’s office before and have a few tattoos, but this was different.

I already knew there was no way I could inject myself so Abe volunteered.  The second week it was just me and Abe so we made the preparations exactly as the nurse taught us and Abe was ready to inject into my thigh.

However, right when Abe would get to the “1” in the countdown  I would swat my hand at him saying that I wasn’t ready and needed more time.

He told me I had to get the shot, so I might as well get it over with.

It sounded reasonable, but fear over took my body. I don’t know how long it took, but eventually I had the shot. Quite a few weeks were like this. My doctor prescribed something to help me relax and I started to have a glass of wine before the shot, neither of which helped that much.

So, I turned to my online support group. I learned of a prescription numbing cream called Emla.

I was able to get a tube of what I started to call “Miracle Cream” before my next injection. I would put some on my thigh (I never was brave enough to use my arms in the year and a half I was on Avonex or do an injection myself) a half hour before my shot and then taped on a piece of saran wrap over the cream.

I know how silly that sounds (and looks!) but it works! I also drew a circle with a pen around the numb area to indicate to Abe where to inject. The cream made all the difference in the world!

Once I started using the cream, my weekly shot became so much more bearable! I wouldn’t feel when the needle would pierce my skin which meant I wouldn’t move my leg from being startled.

Moving my leg made the shot so much worse.  Also, we learned to slowly push the plunger of the medication rather than quickly to get it over with.

I really had wished somehow I could have known about all these tips sooner, but I was so thankful to have the shots become easier!

I encourage anyone to look into this “Miracle Cream!”

About the author: Caroline was diagnosed with MS in 2006. She is currently inspiring those with MS through blogging, her volunteer efforts as a mentor at MS Active Source, her Facebook group; Friends Against the MonSter and also you can ‘like’ Caroline’s page on Facebook right here


About our Co-Founder: With a bachelors in Social Work, Linda is 53 years old, happily married with eight children and 17 grandchildren. Diagnosed with MS in 1995 and now having accepted and truly embraced her new reality, Linda has created She is dedicated to proving that joy can be chosen while living with Multiple Sclerosis. Linda specializes in helping others, especially those with MS attain the lifestyle, independence and happiness amid living with MS.


  1. That’s awesome info Caroline! Thanks for sharing! I’ve been using Copaxone since 2002 now. It was tough going the first year with the injection site reactions but that eventually tapered off. As for the pain of the needle, I’ve found that if I use the highest fat content areas of my body for my injection sites, I barely feel the needle at all.

    I tried the autoject for a while but the sudden impact was more distressing for me than being able to plunge the needle in myself without it. In fact, I learned that if you rotate the needle as you push it into the skin, it breaks the skin far more easily. Most of the time now, between using fatty spots and rotating the needle, I amost never feel it anymore at all.


  2. I had no idea about this cream! My injections are Rebif and the needle isn’t as big so I am not sure it would help alleviate my dread of the shots. But it might be worth a try. I have an appt with a new Neurologist this week so I may mention it.

    As always, thank you for sharing the wealth of info you have learned on this journey. Your info is a treasure to the rest of us!

    • Caroline Kyriakou

      Thank you Yvonne! Best of luck with your appointment! I am not sure how the cream will help a SC shot, but it is definitely worth asking about! Anything to make the shots go a little easier, right!?!

Comments are closed