Multiple Sclerosis and Sex Hormones

The National Multiple Sclerosis society said, “There is a growing body of scientific evidence suggesting that hormones, including sex hormones, may affect and be affected by the immune system. For example, both estrogen and progesterone, two important female sex hormones, may suppress some immune activity. Testosterone, the primary male hormone, may also act as an immune response suppressor. During pregnancy, estrogen and progesterone levels are very high, which may help explain why pregnant women with MS usually have less disease activity.

Kathryn R. Simpson, author of The MS Solution , has attributed MS to hormone insufficiency. She has a wealth of information in her book that you can get here. I’ll be studying and applying the principles I learn here and you can too!

Kathryn suggests we find an advisor and advocate while we go through the start-up phase of detecting and treating our endocrine deficiencies. Finding the right doctor to partner with in this process, she says, will be critical to the success of our therapy.

As the research continues, more will be revealed. “Nancy Sicotte, MD, Rhonda Voskuhl, MD, and colleagues have published results from a small study, funded by the National MS Society and others, suggesting that one year of treatment with a gel containing the sex hormone testosterone (applied to the skin) in 10 men with relapsing-remitting MS resulted in significant improvements in cognitive function and in slowing brain tissue loss. These positive findings were reported in the May 2007 issue of Archives of Neurology.

I always believed that I knew enough to have optimum health, after doing all that I’ve believed and still experiencing MS symptoms, I realize there is more to it! I still have much more to learn!

I have to say, I’m a very happy person and I’m sure that faithfully living out all my beliefs has made me the joyful person that I am. I am completely grateful for everything that I’ve learned. It will be fun to see where the future takes me!


About our Co-Founder: With a bachelors in Social Work, Linda is 53 years old, happily married with eight children and 17 grandchildren. Diagnosed with MS in 1995 and now having accepted and truly embraced her new reality, Linda has created She is dedicated to proving that joy can be chosen while living with Multiple Sclerosis. Linda specializes in helping others, especially those with MS attain the lifestyle, independence and happiness amid living with MS.


  1. Interesting – I have lupus, and being an autoimmune disease, it too is influenced by sex hormones. Great information – stay strong, keep fighting!!

    • Thank you~ I don’t know much about lupus only that it’s like you say, an auto immune disease and that it’s like MS, different for everyone. We’ll both need to stay strong! I look forward to getting to know you!

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