Myelin Can Be Repaired!!! The Myelin Repair Foundation (MRF) is the first multiple sclerosis research organization focusing on the repair of the myelin and have discovered that the myelin can be repaired!
The Foundation understands that just as other cells in the human body can renew and replace themselves, the cells of the brain and spinal cord can also renew themselves, only at a slower rate! (Go figure~ they’re always calling ME slow!)
The five areas that the foundation has been investigating are talked about in this film.
Repair Blood Brain Barrier: A normally robust barrier but with MS is broken down allowing MS T-cells the ability to get past and once inside brain they attack and destroy the myelin. MRF believes closing the holes in the BBB could dramatically reduce MS activity and provide a better environment for myelin repair to take place.
Stimulate Myelin Repair: Oligodendrocytes are the cells that produce myelin and for some reason people with MS are not able to produce the Oligodendrocytes because the signals are not getting to the Oligodendrocytes to repair. MRF thinks that by providing the signals artificially to repair the damaged myelin.
Inflammation Protection: Inflammation Protection: During an MS attack MS T-cells produce toxic chemicals that overload the myelin and prevent the Oligodendrocytes from repairing the myelin.
Immune Regulation: MS T-cells are activated by consuming myelin debris that is produced as a result of the disease actively blocking the receptors on the T-cells that allow this activation reduces the body’s inflammatory immune response, creating a more favorable environment for stimulating myelin repair.
Stimulate Stem Cells: When myelin damages stimulate the production of stem cells which migrate to the site of the injury. The legions prevent those cells from entering the site and repairing the myelin MRF is working to discover the key to understanding enable the stem cells to migrate to the legions to re-myelinate the damaged areas.
Why did the Myelin Repair Foundation choose to focus on myelin repair?
Demyelination is common to all forms of multiple sclerosis. Repairing the myelin damaged by multiple sclerosis will improve signal transmission in the central nervous system and reduce the symptoms of the disease.
You can read updates from the Myelin Repair Foundation right here!